I am having the same problem, I installed the game began playing saved then tried to load the save, I got the same error.
log file
EDuke32 2.0.0devel r3294
Compiled Dec 14 2012 15:20:14
Using C:/duke3d/ for game data
Windows Vista Service Pack 2 (build 6.0.6002)
Initializing DirectDraw...
Searching for game data...
Using "DUKE3D.GRP" as main game data file.
Compiling: GAME.CON (151190 bytes)
Including: DEFS.CON (35992 bytes)
Including: USER.CON (45482 bytes)
GAME.CON: In actor `ORGANTIC':
GAME.CON:3967: warning: found `else' with no `if'.
GAME.CON: In state `pigshootenemystate':
GAME.CON:5890: warning: found `else' with no `if'.
Found 2 warning(s), 0 error(s).
Resizing code buffer to 16189*4 bytes
Script compiled in 77ms, 16181*4b, version 1.4+
2006/11264 labels, 322/2048 variables, 3/512 arrays
125 quotes, 207 actors
Initialized 24.0M cache
Using RTS file "DUKE.RTS".
Initializing OSD...
Initializing DirectInput...
- Enumerating attached game controllers
- No game controllers found
Uninitializing DirectInput...
Executing "settings.cfg"
Disabling desktop composition...
Setting video mode 1280x800 (32-bit fullscreen)
polymost_glreset()
Enabling ATI FBO color attachment workaround.
OpenGL Information:
Version: 3.3.11653 Compatibility Profile Context
Vendor: ATI Technologies Inc.
Renderer: ATI Mobility Radeon HD 3650
gltexinvalidateall()
gltexinvalidate8()
polymost_glreset()
Opened "textures" as cache file
Initializing music...
Initializing sound... 32 voices, 2 channels, 16-bit 44100 Hz
gltexinvalidateall()
gltexinvalidate8()
Cache time: 212ms
E1L1: HOLLYWOOD HOLOCAUST
AMMO FOR PISTOL!
sv_saveandmakesnapshot: snapshot size: 9167976 bytes.
ud: 0 ms
sws: 172 ms
script: 169 ms
animisc: 63 ms
vars: 21 ms
Game Saved
sv_loadsnapshot: snapshot size: 9167976 bytes.
ud: 0 ms
sws: 165 ms
script: 134 ms
animisc: 72 ms
EOF ERR
sv_loadsnapshot: doloadplayer2() returned -7.
Loading save game file "dukesav1.esv" failed (code 5), cannot recover.
Wrote eduke32.cfg
Wrote settings.cfg
polymost_glreset()
polymost_glreset()
Uninitializing DirectDraw...
my system specifications:
OS: Windows Vista Home Premium Home Edition Media Center 6.00.6002 Service Pack 2 (32-bit)
GPU: ATI Mobility Radeon HD 3650
CPU: Intel Core 2 Duo Mobile T5550 @ 1833 MHz
RAM: 3072 MB DDR2-SDRAM
(info from PC Wizard 2012)
I am currently using eduke32 version 3294
last working version: 3271
first broken version: 3278
I hope the extra info helps