For me stuff like the glory hole in the toilet were much more disturbing. Since when is Duke a guy that sticks his dick into literally any opening if it's just there? Sure, you don't need to do it, but it just doesn't fit. I was perfectly fine with the way sexual content was conveyed in Duke3D.
The poop throwing was something that Gearbox probably considered being cool, in the meaning of "Uh-huh, you didn't expect we'd go that far with interactivity in this game, did ya?" Well, needless to say, just being able to do stuff in a game you couldn't do anywhere else before doesn't turn it into a mind-blowing experience.
I just would have liked to witness the designer discussions when they implemented this:
"Hey, got this neat piece of shit here. What could Duke do with that?"
"Ummm... flush it down the toilet?"
"C'mon, dude, you can do that at home at any time."
"Well, errr... he can't eat it, right?!"
"He could put it into his ass. Back to the roots style or something."
"That's a bit sick, man. How about throwing it at walls and smear it everywhere?"
"Nailed it."
Wouldn't be surprised if they spent more time with groundbreaking gameplay mechanics like that rather than a story that makes some kinda sense, weapons not being limited to 2-4 pieces, Duke acting the way he should, avoiding crappy level borders etc.

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