Aside from having his long-awaited sequel turning out like this, the events of this game would've been Duke's darkest hour had DNF been any other game.
The aliens came back hungry for revenge, destroyed everything the protagonist built for the past 12 years in a matter of hours (Lady Killer, Duke Dome, Duke Burger), killed everyone he cared about (the Holsom twins, at least), being unable to save almost everyone he encounters ("Not even I can save you now" in The Hive, among many others) even though they all depended on him to protect them and believed he could do anything, getting knocked out all the damn time, and the President blaming him for the alien attack so logically speaking, the people who lost their family members to Pregnators/Pigcops would be angry at him for letting all this happen.
But since this is Duke Nukem, everyone is happy that he kicked the aliens' asses again and cheered for Duke(inator) to be President. I know he's a badass and all and these things don't bother him, but his adventures turned from happy-family-friendly to bloody-ultra-violent real fast between DN2 and DN3D. Now I wonder if he steals one-liners and has women between his arms and legs every night is because he wants to hide his pain (of that, as well as not getting any good games since Manhattan Project).
